![]() |
|
Posted by - Sleepy Coote on February 13, 2003 at 19:43:54:In Reply to: Re: Optimum pressure caveats II posted by SGS on February 13, 2003 at 11:55:23:
Hi, SGS---more thoughts on the premise of ruling out HB via a breath holding experiment. Namely the short term pressure dynamics of holding one's breath do not really approximate the sustained pressure dynamics of over inflated lungs sustained throughout the night.
This breath-holding experiment relies on the premise that the HB reflex is spontaneous---that it is processed by the brain as an instant and discrete pressure triger. However, when CPAP patients are over pressure, they typically remain so on a prolonged basis. The brain, in fact, just may not be so spontaneous or discrete about the HB trigger. Rather, it may attempt to look for a sustained or accumulated pressure before an adequate HB trigger threshold has finally been perceived.
I am aware that some within the medical community hypothesize that HB is the inhibitory mechanism for pressure-induced centrals, while others contend yet other (non-HB) mechanisms are perhaps more likely candidates. Is there a "winning" or prevailing hypothesis out there as to the cause of pressure-induced centrals that you are aware of?
Thanks for coming out to enlighten us!!
Archived Apnea Forum110 viewing only. To post a new topic go to the Apnea Forum Homepage
|
Copyright ©1995-2005 Sleepnet.com., All rights reserved