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Re: Long-term health Qs

Posted by Kevin (in Walla Walla) on January 07, 2005 at 14:51:09:

In Reply to: Re: Long-term health Qs posted by SGS on January 06, 2005 at 12:59:19:

I think one of the problems is OSA is a fairly slowly progressing disease. Because of this, you may not recognize true sleepyness. That's one of the reasons there is so little correlation between Epworth and SSS scales and MSLT/MWT scores. After 10 years with OSA you may no longer "remember" what its like not to be sleepy, and may in fact feel "normal".

The other factor is that there is no "magic number" in OSA. In diabetes we use the Hemaglobin A1C, in hypertension we use a 5 minute resting BP, for Congestive Heart Failure we can use an Echo and look at the ejection fractions, etc. For apneics there is no decent number to use.

One problem I had with the Barbe article is that the n is very small, only 55, and the time frame is very short, only 6 weeks. The APPLES study that's ongoing will look at 1200+ subjects on real or sham CPAP for 6-7 months.

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