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Re: Beta Blocker, High Blood Pressure and Sleep Apnea


Posted by Been There Done That on May 15, 2000 at 08:34:50:

In Reply to: Re: Beta Blocker, High Blood Pressure and Sleep Apnea posted by RenoTom on May 14, 2000 at 21:24:01:

Could it be that during hypopneas, the heart rate slows due to oxygen desaturation? ACE inhibiters and calcium channel blockers carry a warning to be alert to dehydration, as the loss of blood volume due to dehydration results in a higher concentration of medication in the blood stream, thereby the patient becomes over-medicated and the BP drops too low (been there done that on this one myself). Perhaps there is a similar mechanism at work with beta-blockers: the meds lower the pulse rate, then a hypopnea comes along to lower it further, thus posing a risk to the patient. If someone is fully compliant with xPAP and experiencing no apneas or hypopneas, then use of a beta-blocker would not matter, as the person would not be in a situation to experience abnormally low pulse rate.

Of course, I have no idea when or if pulse rate and/or BP drops during normal sleep or during apneas or hypopneas.

Personally speaking, I can't use beta-blockers--my pulse dropped to dangerously low levels--do quite well on the other meds mentioned above.

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