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Re: Which Anti-Depressants Aggravate Apnea?

Posted by Mark Stevens on August 16, 2000 at 19:13:09:

In Reply to: Which Anti-Depressants Aggravate Apnea? posted by Kev on August 16, 2000 at 15:06:57:

It isn't entirely clear which antidepressants exacerbate sleep-disordered breathing - it's probably more the person than the drug. Tricyclic drugs (Elavil, Pamelor, Doxepin) appear to be worse in this regard, while Wellbutrin and Effexor don't seem so bad.

There are 5 selective serotonin drugs (Prozac, Zoloft, Paxil, Luvox, and Celexa), all of which very occasionally worsen SDB, as can Serzone, trazodone (they don't actually make Desyrel any longer), and Remeron. I doubt anyone knows about this with the MAOI's Nardil, Parnate, and Marplan.

Incidentally, the sleep disorder for which antidepressants appear the worst is repetitive limb movements. It looks as if any antidepressant can worsen this in a fairly large number of those with RLM who takes one.

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