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Posted by richard on January 20, 1998 at 17:37:50:In Reply to: actual affect of meds in RLS posted by Keith Brockmiller on January 20, 1998 at 04:26:27:
A lot of the functions of the drugs prescribed can be found on the links for RLS on the SleepNet home page. I'm not sure about Klonopin (even though my wife takes it for panic disorder), but I believe it works as a serotin-uptake inhibitor, making neural transmission accross synapses less succeptable. Other drugs (sinemet, generic= l-dopa/carbidopa) that have primarily worked for Parkinson's have a primary effect of quiescing the nerve impulses themselves. L-dopa is a neurotransmitter that naturally occurs in human brain chemistry and acts as a neural impulse moderator. The problem with l-dopa is that it tends to have a rebound effect; you may have MORE SEVERE RLS in the late afternoon and early evening. Your physiology also builds up a resistance over time. Physicians prescribing meds usually try to stay with low dosages and possibly combinations of drugs to avoid medication tolerance.
- Re: actual affect of meds in RLS ferdr 1/22/98 (0)
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