Posted by Inna on August 13, 2000 at 16:19:45:

In Reply to: narcolepsy vs. hypersomnia posted by Liz Schmohl on June 29, 2000 at 10:45:18:

Both narcolepsy and hypersomnia clinically manifest as excessive daytime sleepiness.
Narcolepsy is a disorder characterised in markedly abnormal sleep architecture.
There are REM sleep occurence in the inapropriate time - i.e at sleep onset. Two sleep onset REMs on MSLT and mean sleep latency of less than 5 minutes are the diagnostic criteria for narcolepsy. Cataplexy - weakness in some muscles groups with strong emotion - if present is patognomonic for narcolepsy. Night sleep is markedly fragmented with frequent arousals.
In contrast patients with Idiopathic hypersomnia have normal sleep architecture, normal sleep efficiency, normal or increased amount of sleep per night. They are just sleepy during the day, and MSLT mean sleep latency is short (< 5 min), but no SOREMs. Provigil may be useful for treatment

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