Posted by Krishna on April 07, 2003 at 20:44:39:

In Reply to: interesting case...suggestions posted by hari on April 05, 2003 at 18:54:24:

As per Sleep Med Pearls (Berry), benzodiazepines may be effective in attenuating the brain arousal that is believed to lead to hyperventilation, CO2 blow off and thus the next central apnea. What is the general view about using a benzodiazepine such as clonazepam in a low dose (o.25 mg HS) at the start of the study to titrate PAP and then to continue using it regularly with PAP? After all, clonazepam effectively decreases brain arousal in PLMD.

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