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Posted by Natalie on March 22, 2001 at 17:24:04:In Reply to: Natalie RE: REMERON posted by Dave on March 22, 2001 at 07:48:40:
For a majority of people, remeron does make them feel drugged. I had that problem at lower doses, especially in the first week. So you are doing really well to be sleeping somewhat better already. I don't know what the quality of my sleep is exactly, because I have total insomnia without remeron, and have never slept well. Any sleep feels like good sleep to me, although I do still have times when I wake up frequently or have other problems. I am just happy to sleep.
I do know for a fact that 5 days isn't long enough to know much about how it will effect you. It takes several weeks for your blood levels to become steady. If you have depression as well as insomnia, then the depression can continue to effect your sleep. The antidepressant effect usually starts after about a week, but won't reach full effect for 4-6 weeks. The good news is that there are studies showing that depression responds more quickly to remeron than to other antidepressants. If your depression hasn't responded by that time, they usually will increase your dosage.
Remeron generally is most sedating at lower doses. However, it is a better antidepressant/antianxiety drug at higher doses. And, as you said, weight gain is reduced at higher doses. So if you are depressed, higher doses can still help your sleep return to normal even though it is less sedating, and if you are gaining weight trying a higher dose is worth it. I didn't know if I could sleep at 45 mgs because it is less sedating and I have needed huge doses of other drugs to have any response at all. But I haven't had trouble because I am less anxious and depressed than I was at the lower doses, so the need for so much sedation has been cancelled out.
I take 45 mgs, which is less sedating but works the best for me. I take it about 2 hours before I plan to fall asleep, and then I do relaxing things for the 2 hours (or less) it takes to work. It is kind of a pain to have to devote that much time to getting ready for bed, but it is what works, and I'd rather sleep than have 2 extra hours to work. I do not fall asleep unless it is impossible for me to remain awake, which it takes the remeron 2 hours to achieve. When I took 30 mgs I think I took it about 90 minutes before bed.
Hope this helps.
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