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Re: Narcolepsy and ADD- Dopamine

Posted by Dana on February 01, 1999 at 20:48:36:

In Reply to: Re: Narcolepsy and ADD posted by Hope on December 31, 1998 at 11:04:31:

Serotonin does not play a role in Narcolepsy or ADD. Serotonin regulates mood which is why it is so popular these days in the treatment of depression. Narcolepsy and ADD, on the other hand, are related to deficits in the norepinephrine and dopamine systems, norepinephrine regulates the sleep/wake cycles and dopamine is the precursor of norepinephrine and regulates motivation and voluntary movement (excess dopamine = pyschosis; deficient dopamine = Parkinson's Disease) I am not a doctor, but I have been diagnosed with both ADD and narcolepsy and after four years on Dexedrine, it no longer works. Because most doctors would rather sign the script and collect the insurance than research something for which they have no subjective experience, I've been researching this, where do you go after the amphetamines have stopped working? I believe that the root cause of this type of disorder is a deficiency in Dopamine D2 Receptors, which is genetic. Therefore, a Dopamine D2 Agonist (simulator) is needed to receive the Dopamine in the first place. Anyone know of any kind of success with Bromocriptine or Selegiline? In terms of long-term mental health, rather than a quick fix?

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