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Narcolepsy&circadian biological clock?


Posted by Narcolepsy on October 10, 2001 at 21:43:07:

Usually, I begin to suffer from sleep attack more easily at 2 hours after waking up in morning (8:30am--
10: 30am). I can wake up refreshed after having a 15 minutes or a little more nap, but in two or more hours,
I will suffer from sleep attack again,so the time range to occur sleep attack and induced naps possibly are 12:40pm--2:00pm, 3:20pm--3: 50pm, 5:30pm--6:00pm). If I resist nap, the sleepy feeling will be more and more intense (bad !) and I have to doze off even during an important meeting.
I would like know if some friends in the forum have the same symptom that occur uncontrollable sleep attack attacks every 2.5 hours or more. Could you please say something about your related symptom? Do you think that there is a likely link between narcolepsy and circadian biological clock?(--I mean that if impaired circadian biological clock lead to abnormal sleep attack wake-up state and wake-up state is fragmented for it).
Besides focusing on analysis of cataplexy and hyprocretin( many narcoleptic patients without cataplexy have normal hypocretin levels), maybe paying more attentions on the changes of some substances before and after a nap caused by sleep attack, the transition of the function of some cells and molecules that affect sleep-wake state boundary possibly and the link of narcolepsy and circadian biological clockare fascinating subjects in narcolepsy research.
I have asthma besides narcolepsy.

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