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Re: Re: Re: What neurotransmitter changes?

Posted by jeanne on August 11, 2002 at 06:29:52:

In Reply to: Re: Re: What neurotransmitter changes? posted by Bill on August 10, 2002 at 12:25:57:

I just read an article in Newsweek magazine (15 July 01) and they talk about a "sleep-switch" model where hypocretin is the chemical in the hypothalmus most likely responsible for pushing the switch in the direction of wakefulness. The hypothalmus contains the Suprachiasmatic Nucleus (SCN) that interprets signals from the eyes and the pineal gland is regulated by the SCN, which releases melatonin. The article also talks about this sleep "switch" in the hypothalmus as the the "brain of the brain" that is active in sleep, but not while awake and that this "switch" that malfunctions somehow in N holds the key to all sleeping disorders. It was a good article, not much info directly on narcolepsy. There was nothing in this article about any substance or chemical (or neurotransmitter, etc.) that causes drowsiness, other than melatonin. However, I think for PWN, melatonin levels are ok and not involved in our disease process. Yes, I am very interested in talking with you. I'm really interested in research regarding whether PWN had ADD or ADHD prior to diagnosis of N.

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