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Re: Provigil and Elavil?


Posted by Linda P. on August 27, 1999 at 21:05:49:

In Reply to: Provigil and Elavil? posted by Jason on August 26, 1999 at 02:16:24:

My familiarity with Elavil comes from being a psychologist for 25 yrs., with Elavil having been the only antidepressant available at one point in time and still pretty frequently used up until the 80's. It is a tricyclic antidepressant, HIGHLY sedating, with anticholinergic properties (dry mouth and constipation along with the sedation). It suppresses REM sleep, then when you discontinue it you get REM rebound (even more REM than you had before the drug) for a short time. Don't know anything about its interaction with Provigil. However, you're on a very low dose of Provigil along with a highly sedating drug whose sedative effects at the dosage you take can easily last into the daytime hours. I would think to say the least that you are not getting maximum wakefulness from your drug regimen. I am, of course, not an M.D., but I would think you might want to discuss with your M.D. an increase in your Provigil at least up to the standard starting dose of 200 mg. and a decrease in the Elavil (some people can get nighttime sedation on as little as 25 mg.) or a switch to another less intensely sedating nighttime drug. Good luck,

Linda P.

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