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upcomming expirements


Posted by PHILIP on June 21, 2000 at 12:50:22:

Stanford has two types of narcoleptic dogs,the narcoleptic dogs most familiar to us ( dobermans ) are part of a breeding colony that pass narcolepsy on to every generation and have disfunctional hypocretin receptors but they also have some dogs that have sporadic narcolepsy which is probably the same type most humans have ( autoimune B1 0602 ) they are going to inject hypocretin into the dogs that have soradic (autoimune?) narcolepsy to see if hypocretin helps with this type of narcolepsy. The researcher in texas that made the mice that have narcolepsy (because they don't have the gene to make hypocretin in the first place) has injected these narcoleptic mice with hypocretin and it did work. Assuming that the dogs at Stanford that have sporadic narcolepsy have narcolepsy for the same reason most people do (autoimmune? ) this expirement will be important because if it works we will know hypocretin is enough, if it fails I suppose the implication would be tissue destruction in the hypothalamus etc would be why it fails

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